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Turn it upside down and gently pull the plunger out to draw in the prescribed amount of B12 solution into the barrel

Hydroxocobalamin is the preferred agent in this patient population (see separate monograph in Less Common Drugs)

Neurologic manifestations will not be prevented with folic acid, and if not treated with vitamin B12, irreversible damage will result

The C-terminal region (amino acids 176-191) does not participate in growth hormone receptor binding but has been associated with lipolytic activity

Among vitamin B12 deficient older people, high folate levels are associated with worse cognitive function: combined data from three cohorts