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Modulation of multidrug resistance p-glycoprotein activity by flavonoids and honokiol in human doxorubicin-resistant sarcoma cells (MES-SA/DX-5): implications for natural sedatives as chemosensitizing agents in cancer therapy

Studies observed through two-photon imaging that neurons in awake mice preferentially uptake the glucose analog 2-deoxyglucose-IR (2DG-IR) during sensory stimulation, with higher hexokinase expression than astrocytes, indicating that neurons have an intrinsic ability to metabolize glucose through enhanced glycolysis (Tang, 2018

Diabetic wounds exhibit decreased Ym1 and Arginase expression with increased expression of IL-17 and IL-20

Ursolic acid, an inhibitor of TMEM16A, co-loaded with cisplatin in hydrogel drug delivery system for multi-targeted therapy of lung cancer

[DOI] [PMC free article] [PubMed] [Google Scholar] 17.Bmeur C., Vaquero J., Desjardins P., Butterworth R.F

The opportunities and challenges in targeting glutamine metabolism are also discussed
