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Overexpression of MIA3 enhances the tumorigenicity of HCC cells in vivo We further explored the effect of MIA3 on cell proliferation in vivo, for which we established a subcutaneous xenograft model

Starting peptides early in disease course optimizes outcomes

To increase carbon flux to the TCA cycle, we focused on citrate synthase (CS)

One more realistic animal model is that induced by cecal ligation and puncture (CLP), where puncturing the cecum causes the release of fecal material in the peritoneum that results in a polymicrobial peritoneal sepsis

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Jalal S, Fakhri S, Morovati MR, Noori EM, Miraghaee S, Farzaei MH (2018) Evaluation of the protective effect of hydroalcoholic and aqueous extracts of Ulmus minor leaves on ulcerative colitis induced by acetic acid in rats