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2008;295(2):G294304

Mu opioids and their receptors: evolution of a concept

demonstrated that intracellular glucose, redox state, membrane potential, ROS, and drug uptake are suppressed in gentamicin-resistant Vibrio alginolyticus relative to control cells 14
2024;283(Pt 2):137846
Haem binding in NPAS2 enables carbon monoxide (CO) sensing, where CO binding in the presence of haem prevents NPAS2DNA interactions [82]

Therefore, these effects are not only local, but the microenvironment that is created maintains M1 activation leading to further, widespread damage
