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In case of persistent HH under DAs therapy, clomiphene citrate (selective ER modulator that antagonizes estrogen action on the hypothalamus) is a possible strategy for gonadotrophic axis recovery: clomiphene increases testosterone concentration and improves sperm motility independently of PRL normalization (233)

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For traceability, label all aliquots with compound name, concentration, reconstitution date, and operator initials

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