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The Korsmeyer-Peppas model is a widely used mathematical model that describes the release of drugs from nanocarrier systems, particularly in the context of controlled release formulations

doi: 10.1016/j.yexmp.2006.02.006

A one-week titration at 1 mg may improve tolerability before advancing to the full 2 mg dose

Given the high prevalence of hypogonadism associated with genetic factors, diabetes, and excess weight in Gulf countries (KSA, UAE, Oman), regular monitoring by a specialist is a key requirement for ensuring both treatment safety and effectiveness

44 Significantly higher glutathione peroxidase activity has been reported in a group of patients with SLE who tested positive for anticardiolipin and in patients with SLE whose Systemic Lupus Erythematosus Disease Activity Index (SLEDAI) scores were higher than 3, compared to patients with SLEDAI less than 3

Kitada et al., 2020