l carnitine mechanism fatty acid transport L-Carnitine | Linus Pauling Institute CARNITINE HOMEOSTASIS, MITOCHONDRIAL FUNCTION, AND

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Significant targets and the effects of PKGI in SMC are activation of myosin light chain phosphatase, inhibition of PLC, inhibition of the IP 3 receptor, inhibition of plasma membrane localized L-type Ca 2+ channels, and activation of plasma membrane localized calcium-activated K + channels (commonly called the big potassium, BK, channels)

Collectively, understanding the relationship between acylcarnitine levels in different tissues and how these reflect mitochondrial (as well as peroxisomal) dynamics warrants further investigation

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