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The 12mg weekly maintenance dose produced the greatest weight reduction (-24.2%) in Phase 2 trials

The overall orientation shifted from CuA towards the L4 region

Trease GE, WC Evans (1983) Pharmacognosy Balliere

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Likewise, polyphenols or omega-3 fatty acid combinations with chemotherapy are studied for pharmacodynamic synergy by means of endpoints such as tumour volume reduction, progression-free survival and amelioration of chemotherapy-induced toxicity along with quality-of-life enhancement, keeping a close watch for antagonistic interactions or organ-specific adverse effects (234)

We knew that, that if you put diabetics on this drug, they would lose weight