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50 & Target [2] In Vitro Isotretinoin (13-cis-Retinoic acid) may act as a pro-drug that is converted intracellularly to metabolites that are agonists for RAR and RXR nuclear receptors [1]
Arthritis Care Res 70:481485
It is worth noting that GPX4, as a selenium protein, depends on the synthesis of selenium cysteine (Zheng and Conrad, 2020)
Recent studies and case reports have raised concerns about a possible link between COVID-19 vaccination and the development of GD (11, 21)
Mikles, M.R., Vaccaro A.R., C.M
