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GSH artificially oxidizes during sample handling producing GSSG Most of GSH to GSSG ratios reported in the literature are erroneous Immediate SH alkylation with N -ethylmaleimide is mandatory Acknowledgments This work was supported by grants to PF from US National Institutes of Health (NIH) National Center for Complementary and Alternative Medicine (NCCAM) (grant no

A small, short clinical study comparing 4 weeks of erdosteine therapy at either 300 mg BID or 300 mg TID in 24 patients with COPD, demonstrated a decrease in 8-isoprostane levels compared to baseline values

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A carefully planned diet with an appropriate intake of antioxidant-rich food and physical activity might protect against many pathologies, particularly diabetes, obesity and cardiovascular complications [[15], [16], [17]]

& Beck-Peccoz, P

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