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Vertebrate animal models Toxin-induced models Quinolinic acid (QA) model Quinolinic acid selectively targets medium spiny neurons (MSNs) in the striatum, mimicking HDs excitotoxic mechanisms (Ca 2 dysregulation, ATP depletion) and manifesting an early-stage hyperkinetic symptoms (Bordelon et al
Wiley, New York Leopold DA (2009) Pre-emptive blood flow
