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Comparison of drug metabolism and its related hepatotoxic effects in HepaRG, cryopreserved human hepatocytes, and HepG2 cell cultures

(2) testing the safety and efficacy of this delivery in both rats and nonhuman primates

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doi: 10.1017/S0007114511005484 [DOI] [PubMed] [Google Scholar] 48.Stewart RJ, Askew EW, McDonald CM, Metos J, Jackson WD, Balon TW et al

Membrane peroxidation and methemoglobin formation are both necessary for band 3 clustering: Mechanistic insights into human erythrocyte senescence

However, it is observed that the developmental toxicity of DMSA, mediated predominantly via altered copper metabolism, persists with MiADMSA