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Dihydrochalcones are flavonoids that are uncommon in nature, and phlorizin, the main active ingredient of the Tibetan medicine Malus toringoides (Rehd.) Hughes and Lithocarpus polystachyus , belongs to this category [189]
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Other ingredients discovered by the FDA include phenolphthalein, blood pressure treatments, seizure medications, and other mislabeled products
JACC Basic Transl Sci (2018) 3:50317

The opposing effect of AA and BA/MS on stress tolerance and the apparent health and wild-type-like basal stress tolerance of young LRO mutants suggested it is not merely a deposition of toxic metabolites in gut granules, but their active involvement in an organismal response to stress