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When subjected to rigorous clinical trials, most drugs fail

10.1002/dvdy.21805 46 ChoiK.-S.HarfeB

8a), indicating that while the Cagri-CTR complex can sample this conformation, it occurs at lower frequency than rAmy-CTR

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While selenium deficiency is a major etiological factor of Keshan disease (54), the seasonal and annual variation in disease occurrence suggested that other factors, especially an infectious agent, might be involved in addition to selenium deficiency (55)

In dogs living in a thermoneutral environment with a 12-h light period/a 12-h dark period, their heat production rate varies with a circadian rhythm, with the lowest rate in the morning (e.g., 124 kcal/kg BW 0.75 /day in beagles), gradually increasing to a maximum in the evening (e.g., 195 kcal/kg BW 0.75 /day in beagles), and then declining through the night (Besch and Woods 1977)