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In both lower and higher eukaryotes, the initiation of autophagy requires the assembly of specific protein complexes: (1) the Atg1-Atg13-Atg17 (ULK1-Atg13-FIP200 in mammals) kinase complex, which initiates phagosome formation at the phagophore assembly site (PAS, an Atg8-rich cytoplasmatic site) (Kabeya et al., 2005

The cycle time was 0.6 s

Johns wort: Activated PXR induces CYP3A4, which can metabolize steroids found in oral contraceptives

Sanz Y (2007) Ecological and functional implications of the acid-adaptation ability of Bifidobacterium: a way of selecting improved probiotic strains

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ER stress regulates LTC 4 receptors expression and localization ER stress also regulated the expression of the two LTC 4 receptors, CysLTR1 and CysLTR2, initially attenuating their level and upregulating it at the late, death-promoting phase of the UPR (Fig
