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Research Use Only This product is intended for research purposes only and is not for human consumption, therapeutic use, or diagnostic applications

In such studies, high Zn concentrations repressed the lipopolysaccharide (LPS)-induced activity of several PDE isoforms (e.g., PDE-1, PDE-2, and PDE-4) in monocytes, increasing cGMP levels

The Alzheimer's therapeutic PBT2 promotes amyloid-beta degradation and GSK3 phosphorylation via a metal chaperone activity

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