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Furthermore, signal transducer and activator of transcription 3 (STAT3) can inhibit the mTOR/HIF-1 pathway by activating AMP-activated protein kinase (AMPK), leading to reduced cell proliferation and increased apoptosis (38)

doi: 10.1002/ana.10248

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Particularly in medicine, NPs offer numerous advantages such as enhancing drug stability, solubility, and concentration, as well as prolonging drug release while minimizing adverse effects on cellular growth and metabolism [253]