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Intracerebroventricular administration of miR-103a-3p reduced levels of malondialdehyde, protein carbonyl, nitrite, caspase-3, caspase-1, TNF, and NLRP3, restoring SIRT1 and BDNF expression and reducing ER stress by decreasing PERK, CHOP, GRP78, improving learning and memory [141]

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Measurement of urinary tetranor-PGDM and tetranor-PGEM concentrations Urinary concentrations of tetranor-PGDM and tetranor-PGEM were measured by liquid chromatography with tandem mass spectrometry (API3000 system