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Definitions of hypertension, hyperuricemia, dyslipidemia and diabetes According to the Japanese guideline for hypertension 21 , individuals with at least one of the following findings are diagnosed as having hypertension: (1) office blood pressure levels of 140/90 mmHg or more and/or (2) out-of-office blood pressure levels of 135/85 mmHg or more

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Either sex is affected equally and the condition can occur at any age, the median age is 40 years

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Due to the poor bioavailability and interconversion of these precursors, more potential NAD + precursors and intervention strategies are sought that have higher potency and stability