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M7510, Thermo Fisher Scientific) for 1 h at 37 C

Since tirzepatide may slow gastric emptying as part of its mechanism of action, patients with pre-existing severe gastroparesis could experience worsening of symptoms, including nausea, vomiting, and potential complications related to delayed gastric emptying

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These calculations use 15-30mcg/kg as the reference range

[91], their tuneable PL enables high contrast fluorescence imaging, however, challenges relating to in vivo stability, biodistribution, and long-term safety remains key barriers to clinical translation [91]