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(2009) Chloroquine resistance before and after its withdrawal in Kenya

Injection site rotation prevents localized irritation
It was assumed to be the result of some combination of high amounts of stomach acid and certain irritating foods in the stomach that over time wear away at the stomach lining

Nowak LG, Bullier J
For general skin anti-aging, systemic subcutaneous injection at 1 to 2 mg/day combined with topical application achieves the best tissue-level collagen response
