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However, dopamine decreased the production of NO and NO synthase in LPS-stimulated primary rodent microglia as well as N9 and BV2 murine microglia through D1- and D2-like receptors (Chang and Liu, 2000

BMJ Open 8 , e022404 (2018)

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The toxic effect of NO is in fact closely related to the formation of the secondary RNS ONOO - , which occurs when NO is overproduced