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Between 50% and 57% of those on the highest dose achieved 20% or greater weight loss

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Yanagie et al, 2009)

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It acts as a signaling molecule that: Activates tissue repair pathways Stimulates collagen and glycosaminoglycan synthesis Promotes angiogenesis Modulates inflammation via NF-B suppression When endogenous levels fall, regenerative capacity falls in tandem

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A useful overview of that link is in microbiota-immune, which explains how microbes steer immune behavior

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