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The expression of NtMEK2 DD induced the generation of hydrogen peroxide and up-regulated the expression of defense-related genes including PR- genes, peroxidases and GSTs including GSTTU4 and GSTTU12 (Jeong et al., 2008)

, 33 , 435-454, Kumar, B., Koul, S., Khandrika, L., Meacham, R

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This protects living cells and tissues from oxidative damage and makes it a key antioxidant in the fight against several ROS-mediated diseases, including cancer, Alzheimers disease, and atherosclerosis

Overall Survival and Long-Term Safety of Nivolumab (Anti-Programmed Death 1 Antibody, Bms-936558, ONO-4538) in Patients With Previously Treated Advanced Non-Small-Cell Lung Cancer