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Budhathoki, S

High Dose (80-120+ mcg/day): Doses exceeding 80mcg per day are typically reserved for short-term, highly specific, and advanced research protocols
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All of these can lead to anorexia, which in turn can lead to HL

Pincus T: Folic and folinic acid supplementation reduces methotrexate gastrointestinal side effects in rheumatoid arthritis

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