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Cleavage of the Z protecting group afforded dipeptide 5

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Some of the latter are not considered true neoplasms: histiocytoma is in fact a Langerhans cell proliferation that regresses spontaneously and reactive cutaneous histiocytosis is considered to be a reactive inflammatory response of interstitial dermal dendritic cells, based on the reported spontaneous regression of some cases and on the good response to several immune-modulatory drugs

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