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Via activating AMPK and suppressing pro-inflammatory cytokines (IL-6 and TNF-), AC can ameliorate renal inflammation and fibrosis induced by high glucose in HK-2 cells (Ahmed et al

Interestingly, in tumorigenesis these enzymes protect from cancer development but once this fails GSTs are essential for ensuring the survival of tumor cells [91]

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They tend to provide the backbone of most organic molecules

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