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BCAAs (leucine, isoleucine, and valine) and lysine are catabolized to acetyl-CoA that can potentially be utilized by HATs 22

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Interestingly, pyruvate kinase liver and red blood cell (PKLR) expression is inhibited in liver-specific Keap1 -null mice [82]

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By contrast, CISD2 inhibition accelerates sulfasalazine-induced ferroptosis by increasing mitochondrial ferrous iron and lipid ROS levels (33)