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Niacin and niacinamide are both forms of vitamin B3 but have slight structural differences

doi:10.1002/14651858.CD004655.pub3

Mapping of early signaling events in tumor necrosis factor alpha-mediated lipolysis in human fat cells

Subsequent post hoc analysis demonstrated a significant reduction in mean MOG expression in slices treated with CPZ in comparison to untreated slices (Untreated: 100% 8.5%, CPZ-treated: 53.08% 2.52%, p = 0.00002)

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The Obesity Medicine Association does not list them among evidence-based obesity treatments