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ALCAR should be avoided in people with hypothyroidism, because it can inhibit T3/T4, and in individuals with severe underlying mental health issues, because it can trigger psychosis
Muscle Nerve 1991;14(7):598-604
(2018) 7:e34408

Skeletal muscle carnitine loading increases energy expenditure, modulates fuel metabolism gene networks and prevents body fat accumulation in humans

Mitochondria produce ROS during adenosine triphosphate (ATP) generation, with some electrons leaking from the electron transport chain (ETC), which subsequently leads to superoxide anion production [66]

While choline shows therapeutic potential, such as reducing inflammation and supporting cognitive and liver health, it can also contribute to disease, including increased risk of cardiovascular events or cancer progression
