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In the Liverpool cohort, plasma metformin levels were also measured

Gu et al

Clinical and applied thrombosis/hemostasis

Thanks to their expanded interface with the target protein, peptide PROTACs demonstrate superior potency, higher selectivity, and reduced toxicity compared to low molecular weight compounds, especially when targeting proteins lacking well-defined binding pockets (Kargbo, 2019)

They make it water soluble and help you excrete it through urine
