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Description
Tirzepatide activates GLP-1 and GIP receptors to reduce appetite and slow gastric emptying, creating a caloric deficit through reduced intake

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Protects against insulin resistance: It helps protect against age, diet, and obesity-dependent insulin resistance

It's metabolized and cleared by the kidneys, and while preclinical data shows promise for kidney recovery, comprehensive human safety isn't established

Nicotine can also acutely raise blood pressure and heart rate

An estimated 20% of dogs over age one have some form of osteoarthritis and in dogs over seven, that number climbs to over 65%
