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Higashida, H
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GHK-Cu stands for Glycyl-L-Histidyl-L-Lysine-Copper, a naturally occurring copper peptide found in human plasma, saliva, and urine
Treatments in these co-cultures included PBS as a control, FOXO4-DRI at 50 M, hydrogen peroxide (H2O2) at 50 M to induce senescence, and a combination of H2O2 with FOXO4-DRI
This therapy utilizes a small molecule known as 5-Amino-1MQ, which targets an enzyme called Nicotinamide N-methyltransferase (NNMT)
