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Pettegrew JW, Klunk WE, Panchalingam K, et al

In accordance with the effects observed on muscle atrophy, monotherapy with rifaximin and L-carnitine prevented the CDAA-induced decrease in forelimb grip strength, and the combination of these agents augmented these preventive effects after 12 weeks (Fig

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Biochim Biophys Acta Mol Cell Res 1863:24222435

XuSWaddellJZhuWShiDMarshallADMcKennaMCet al

Our findings may indicate reduced CPT-I activity in the patient group, which is essential for the -oxidation of long-chain fatty acids, facilitating their conversion into acylcarnitines for transport from the cytosol into the inner mitochondrial matrix [17,18]