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CLINICAL OPPORTUNITIES Pharmacological strategies to inhibit glutamine metabolism in cancer cells As previously reviewed, glutamine metabolism exhibits pleiotropic effects on cancer cell signaling and proliferation and therapeutic suppression of glutamine metabolism is considered to be an attractive anticancer strategy (Table 1)

However, physicians noticed these patients started losing weight when taking this medication

Ann Allergy Asthma Immunol 102(2):116-20

The elevated production of OPT is typically observed in APAP-overdosed mice [144], in patients with hepatic injury [142], and in fasted mice [145]

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2) Dihexa was shown to improve cognitive impairments and recover memory by inhibiting inflammation and decreasing neuronal loss by affecting the PI3K/AKT signaling pathways