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Statistical analysis was performed using GraphPad Prism 10.2
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The IR-A isoform is most important in the processes of prenatal growth and development, whereas the IR-B isoform predominates in the metabolic processes regulated by insulin in the adult
With the bodys aging or metabolic disturbances, the glycation process increases with a concomitant weakening of the elimination of glycated proteins
Statins inhibit the rate-limiting step of cholesterol biosynthesis, blocking the reduction of HMG-CoA reductase to mevalonate
