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The ferroptosis inhibitor Liproxstatin 1 can reduce brain edema and BBB permeability caused by TBI, improve motor and learning and memory impairment caused by TBI in rats, and significantly improve anxiety and cognitive function caused by TBI (Xie et al., 2019)

Higher zinc concentrations, however, can suppress the release of other proinflammatory cytokines, such as IL-1 and TNF-, by inhibiting phosphodiesterase activity, thus modulating the inflammatory response [243]

N., Velecu, I

N.et al (2024)

[PubMed] [Google Scholar] 16.Arrick BA, Griffith OW, Cerami A

Bauer TM, Murphy E (2020) Role of mitochondrial calcium and the permeability transition pore in regulating cell death