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(2020) reported a significant risk association between DM2 in severely obese individuals and subsequent diagnosis of ASD (HR 2.28, 95% CI: 1.18, 4.41)

Patients taking anticoagulants should be closely monitored for changes in prothrombin time or INR, and dosage adjustments may be necessary

Liver-specific loss of long chain acyl-CoA synthetase-1 decreases triacylglycerol synthesis and beta-oxidation and alters phospholipid fatty acid composition

Both were assigned as Key Clinical variants, although clinical correlation is somewhat borderline

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