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Front Endocrinol (Lausanne) (2017) 8:109

For targeted therapeutic support during severe symptom flares or intense detoxification protocols, some functional medicine providers may recommend temporarily increasing the dose to 300 mg or 400 mg per day, though this should always be done under medical supervision

Drug repurposing: a futuristic approach in drug discovery

3, 4 5.2 Hypoxic Conditions Cells shift their metabolic processes under hypoxic conditions to survive in environments with low oxygen

Arteriosclerosis thrombosis Vasc Biol (2003) 23(12):217884
