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Alpha thalassemia

The decrease of GDH1 activity limits the flow of carbon into TCA cycle (59)

To further assess the role of mitochondrial lipid peroxidation in driving vulnerability to ferroptosis in N1IC cells we used a battery of ROS scavengers and ferroptosis inhibitors with different mechanisms of action

doi: 10.1186/s41100-018-0195-2

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Increased [ 35 S]-glutathione binding sites in spinal cords from patients with sporadic amyotrophic lateral sclerosis