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The transcription factor ISL2 can regulate the expression of metabolic genes and affect OXPHOS [45]

This is because SUVs can entrap at lower lipid volume i.e., 0.20.8 l/mol than compared LUVs and MLVs which show higher lipid entrapment volumes i.e., 130 l/mol

The PI3K/Akt signaling pathway regulates Nrf2 activity through GSK-3, a serine/threonine kinase encoded by the alpha () and beta () genes

A deep understanding of these interactions is therefore paramount for rational nanozyme design (including size, morphology, component doping and surface modification), optimization of therapeutic windows, and minimization of off-target effects in future translational applications

It relies on glutathione to maintain its transparency and proper hydration levels