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Literature has shown that the expression of cellular protective enzymes increases in CRS patients, indicating that oxidative stress plays a role in the pathophysiology of CRS

Walski, T., Dbrowska, K., Drohomirecka, A., Jdruchniewicz, N., Trochanowska-Pauk, N., Witkiewicz, W., & Komorowska, M

Therefore, metformin can be used in renal transplantation setting but it remains unclear whether addition of this drug during machine perfusion results in improved organ quality after transplantation (112)

Harrell CRN, Jovicic V, Djonov V, Volarevic

Nutrition and the prevention of cataracts

In ovariectomized Wistar rats, colonic paracellular permeability was increased significantly and this was reversed by estrogen treatment (oestradiol benzoate) [89]