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H 2 S exhibits the dual vascular effects of vasoconstriction and vasodilation depends on the vascular district, the endothelium conditions, the H 2 S concentration and the method of precontraction 125

However, conventional oral exogenous anti-inflammatory medicine includes glucocorticoids, nonsteroidal anti-inflammatory drugs (NSAIDs), which are unable to penetrate the joint space [119, 120]

[DOI] [PubMed] [Google Scholar] 54.Guevara-Campos J., Gonzalez-Guevara L., Guevara-Gonzalez J., Cauli O

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Ultimately, integrating theranostic capabilities, where delivery systems also provide realtime monitoring of drug release or disease activity, could further transform personalized periodontal therapy
