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It is apparent that oxidative stress is one of the main drivers of mitochondrial dysfunction in FRDA

doi: 10.1007/s00383-008-2123-y

However, this adaptation period may vary from user to user as everyones body responds differently to creatine supplementation

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J Food Sci Nutr 2(1):18 Stuehr DJ, Griffith OW (1992) Mammalian nitric oxide synthases
