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Wild blueberry extract, evaluated by Whyte et al., was shown to improve episodic memory and reduce systolic blood pressure, demonstrating its dual cognitive and cardiovascular benefits (Whyte et al., 2018)

Knockout of prolyl hydroxylase domain-containing protein 2 (PHD2) stabilized HIF-1 protein and activated HIF-1 signaling, which transcriptionally upregulated glutaminase 1 ( GLS1 ) expression leading to a decrease in ROS production and increases in cellular GSH levels, GSH/GSSG, and cell survival in murine periosteal progenitor cells, suggesting that HIF-1 signaling promotes glutaminolysis to provide glutamate for GSH synthesis (96)

doi: 10.2741/A812

The involvement of oxidative stress in the breakdown of immune tolerance is another crucial mechanism in the pathogenesis of autoimmune diseases

0.5 mg/g animal weight) was realized 1 h before killing

Alterations in the gut microbiome together with lymphocytes production of inflammatory cytokines, also sustained by viral infection, can lead to the vasculitis and thrombosis observed in patients with COVID-19 (Mnkemller et al., 2020