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Description
Endocr Relat Cancer (2013) 20:495505
Proven effective in IBD and ulcer healing
SNPs in these genes can influence the conversion of cobalamin into its active forms (methylcobalamin and adenosylcobalamin) as well as the homocysteine metabolism pathway
82,83 As a classical effector of RNAi, siRNA induces gene silencing by blocking mRNA translation
Although it entered phase 1 trials in consideration as a treatment of ulcerative colitis, it has not been approved by the US Food and Drug Administration (FDA) for medical use, and data on human subjects is lacking
But its not quite that simple
