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Description
Alterations in m6A dynamics have been implicated in heart failure and may influence the response of cardiac and endothelial cells to inflammatory stress, representing a novel frontier in understanding the molecular underpinnings of SRMI (108, 109)

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P228 Hillman C

(2022) developed a CRISPR/Cas14-based aptasensor with nanomaterials to enhance fluorescence signals, enabling highly sensitive detection of microcystin-LR for environmental monitoring

In this binding mode, hydrogen bonds of Tyr111 and Gln207 to the carbonyl oxygen atoms of 4HNE, NE, and EA could orient the substrates and enhance their electrophilicity to promote conjugation with glutathione
