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Its job is specific: it inhibits an enzyme called NNMT nicotinamide N-methyltransferase that becomes overactive in fat tissue, especially as we age

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However, they are not a direct fat-burning treatment and work best alongside diet and exercise

(All-cause mortality is a statistic researchers use to measure the risk of death from any cause.) The connection might have been because people with higher levels of vitamin B12 tend to consume higher amounts of animal products that carry saturated fat and higher saturated fat intake

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A review of its contribution to the management of obesity