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Pregabalin is an alpha 2 delta ligand which decreases the pain by modulating calcium channel activity of the nerve cells

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Trends Pharmacol Sci 27:63945, PMID: 17056127 Andreyev AY, Kushnareva YE, Starkov AA (2005) Mitochondrial metabolism of reactive oxygen species

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The symptoms that improved first were urgency and frequency of urination

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