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Glutamate Neurotransmission In the central nervous system (CNS), the balance between excitatory and inhibitory neuronal connections is essential for proper function

It is the only biologically active form in humans

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Furthermore, TMAO activates astrocytes to secrete pro-inflammatory mediators, leading to neuroinflammation (Heneka et al., 2010

Administration of Lcarnitine resulted in a restoration of normal VPA metabolism
